<scp>TRPM3</scp> activation causes <scp>CGRP</scp> release in trigeminal neurons: Implications for migraine mechanisms
TRPM3 activation triggers CGRP release and vasodilatation. The findings that TRPM3 induced CGRP release support further investigation of TRPM3 as a therapeutic target for migraine.
Authors
- Mette Nyholm Jensen (ORCID: https://orcid.org/0009-0000-6792-2200)
- Jacob C. A. Edvinsson (ORCID: https://orcid.org/0000-0002-4397-3326)
- Lars Bøgeskov Nielsen (ORCID: https://orcid.org/0000-0002-9008-7546)
- Connar Stanley James Westgate (ORCID: https://orcid.org/0000-0001-5066-8306)
- Lars Edvinsson (ORCID: https://orcid.org/0000-0002-1805-1346)
- Kristian Agmund Haanes (ORCID: https://orcid.org/0000-0001-5182-8957)
- Philip Victor Reducha
- Spyridoula Kazantzi
- Sofia Lyng Wæver
- Tanja Lylloff
Institutions
- University of Copenhagen (DK)
- Lund University (SE)
- Glostrup Hospital (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Technical University of Denmark (DK)
Publication Details
- Journal
- Headache The Journal of Head and Face Pain
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1111/head.15082
- Citations
- 2
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94