Adrenergic G protein-coupled receptors in liver physiology and pathology: research advances and clinical implications
The liver, key for metabolism and homeostasis, sees growing focus on adrenergic GPCRs (α1/α2, β1/β2/β3; activated by adrenaline/noradrenaline). These receptors affect liver physiology/pathology and are treatment targets. This review explores their roles/mechanisms in liver diseases to aid research, clinic, and precise care.
Authors
- Yashan Wang (ORCID: https://orcid.org/0000-0003-2487-3829)
- Yingyong Hou (ORCID: https://orcid.org/0000-0001-9156-2305)
- Jing Xi (ORCID: https://orcid.org/0000-0003-0881-2356)
- Mao Hu (ORCID: https://orcid.org/0000-0001-5491-8392)
- Yanbiao Fu
- Yun Xue (ORCID: https://orcid.org/0000-0002-0619-9319)
- Zhuoyue Gou
- Yi Li (ORCID: https://orcid.org/0000-0002-2092-4505)
- Yang Yu (ORCID: https://orcid.org/0000-0002-0043-0890)
- Rongchun Xing
Institutions
- China Three Gorges University (CN)
- Yichang Central People's Hospital (CN)
- Qiqihar Medical University (CN)
Publication Details
- Journal
- npj gut and liver.
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1038/s44355-025-00042-y
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00