Extracellular vesicles from primed Hoffa’s fat pad mesenchymal stem/stromal cells in osteoarthritis therapy: effects on cells critical to osteoarthritis progression
HFP-MSC-EVs may have therapeutic potential mediated by attenuating inflammation and downregulation of catabolic enzymes in cells critical to OA progression.
Authors
- Denisa Harvanová (ORCID: https://orcid.org/0000-0002-3038-7520)
- Stefan Nehrer (ORCID: https://orcid.org/0000-0001-8008-2226)
- Karina Kramer (ORCID: https://orcid.org/0000-0002-9720-7598)
- Zsombor Lacza (ORCID: https://orcid.org/0000-0002-6776-9530)
- Slavomira Gulová (ORCID: https://orcid.org/0000-0001-8911-3199)
- Andrea De Luna (ORCID: https://orcid.org/0000-0003-1937-0186)
- Alexander Otahal (ORCID: https://orcid.org/0000-0003-3705-0039)
- Markus Rothammer
Institutions
- Semmelweis University (HU)
- Universität für Weiterbildung Krems (AT)
- University of Pavol Jozef Šafárik (SK)
- Univerzitná Nemocnica Louisa Pasteura (SK)
- Hungarian University of Sports Science (HU)
- Universitätsklinikum Krems (AT)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1186/s13287-025-04679-7
- Citations
- 2
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.34