Factors influencing the quality of life following posterior approach surgical treatment in adolescents with idiopathic scoliosis: A 2-year follow-up study
Surgical intervention is the preferred approach to prevent further progression of deformity for patients with adolescent idiopathic scoliosis (AIS); among existing surgeries, posterior spinal fusion is predominant. The minimal clinically important difference (MCID) of the total score of the Scoliosis Research Society (SRS)-22r questionnaire is an increase of ≥ 0.4 in surgically treated patients. However, to the best of our knowledge, there is no research exploring the factors influencing SRS-22r total scores exceeding MCID at 2 years postoperatively. Patients who underwent posterior spinal fusion between February 2019 and November 2023 and had a minimum follow-up duration of > 2 years were included. The radiological data and SRS-22r scores were assessed preoperatively and postoperatively. Based on the SRS-22r total scores, the patients were divided into two groups: ‘I’ = Improvement group (∆ Score ≥ 0.4) and ‘NI’ = Non-improvement group (∆ Score < 0.4). Demographic characteristics, radiographic data, and SRS-22r scores were analyzed using chi-square tests and t-tests for comparison. Multivariate logistic regression analysis was used to determine influencing factors. A total of 66 patients with AIS underwent posterior spinal fusion surgery were included in the study. The major Cobb angle decreased from 52.9 ± 12.3° preoperatively to 12.3 ± 8.6° (p < 0.001) at 2 years postoperatively, while the SRS-22r total score improved from 3.9 ± 0.4 to 4.2 ± 0.5 (p < 0.001). Overall, 32 of 66 of patients (48.5%) achieved MCID. Preoperatively, the Improvement group trended toward a larger Cobb angle (p = 0.042). Postoperatively, patients who achieved a greater Cobb angle correction in degrees were more likely to attain the MCID (p = 0.003). Postoperative MCID attainment in patients with AIS is influenced by both the preoperative Cobb angle and the degree of its surgical correction.
Authors
- Di Liu (ORCID: https://orcid.org/0000-0002-5803-7223)
- Nan Wu (ORCID: https://orcid.org/0000-0002-9429-2889)
- Aoran Maheshati (ORCID: https://orcid.org/0000-0001-8445-1869)
- Xueyi Zhang (ORCID: https://orcid.org/0000-0001-8097-112X)
- Jianguo Zhang (ORCID: https://orcid.org/0000-0003-3129-5190)
- Zhengye Zhao (ORCID: https://orcid.org/0000-0002-1663-0467)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1186/s13018-025-06225-w
- Primary Topic
- Scoliosis diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Chinese Academy of Medical Sciences
- Peking Union Medical College Hospital
- National Key Research and Development Program of China