Association of ankle-brachial Index with coronary and extra-coronary calcification in older adults: ARIC study
Low ABI was most robustly associated with CAC. Its association was weaker for thoracic aorta calcification and weakest for valvular calcification. These findings further support distinct pathophysiology of calcification across vascular beds and cardiac valves.
Authors
- Michael Joseph Blaha (ORCID: https://orcid.org/0000-0001-5138-9683)
- Jeremy Van’t Hof (ORCID: https://orcid.org/0000-0002-9982-3685)
- Michelle L. Meyer (ORCID: https://orcid.org/0000-0001-7085-3154)
- Kenneth R. Butler (ORCID: https://orcid.org/0000-0003-3198-8835)
- Hirofumi Tanaka (ORCID: https://orcid.org/0000-0002-1780-7471)
- Kentaro Ejiri (ORCID: https://orcid.org/0000-0001-6645-2075)
- Timothy M. Hughes (ORCID: https://orcid.org/0000-0002-2919-7199)
- Miguel Cainzos‐Achirica (ORCID: https://orcid.org/0000-0002-8073-2337)
- Yejin Mok (ORCID: https://orcid.org/0000-0002-8511-604X)
- Candace M Howard-Claudio
- Eyram Cyril Bansah (ORCID: https://orcid.org/0000-0002-6752-7507)
- Kunihiro Matsushita (ORCID: https://orcid.org/0000-0002-7179-718X)
- Esther Kim (ORCID: https://orcid.org/0000-0003-0911-9246)
Institutions
- University of North Carolina at Chapel Hill (US)
- Austin College (US)
- Houston Methodist (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Jackson Memorial Hospital (US)
- University of Mississippi Medical Center (US)
- Methodist Hospital (US)
- Minneapolis Heart Institute Foundation (US)
- University of Minnesota Medical Center (US)
- Wake Forest University (US)
- The University of Texas at Austin (US)
Publication Details
- Journal
- European Heart Journal Open
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1093/ehjopen/oeaf133
- Citations
- 1
- Primary Topic
- Peripheral Artery Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- National Heart, Lung, and Blood Institute