Ticept: Wideband Electrical Properties Tomography by Tissue Composition Assessment With Quantitative 1$$ {}^1 $$H 23$$ {}^{23} $$Na 39$$ {}^{39} $$K Multinuclear MRI
We presented the feasibility of estimating dielectric properties over a wide frequency band with quantitative MRI, leading to a new method: <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:semantics> <mml:mrow><mml:msup><mml:mo> </mml:mo> <mml:mrow><mml:mn>1</mml:mn></mml:mrow> </mml:msup> </mml:mrow> <mml:annotation>$$ {}^1 $$</mml:annotation></mml:semantics> </mml:math> H <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:semantics> <mml:mrow><mml:msup><mml:mo> </mml:mo> <mml:mrow><mml:mn>23</mml:mn></mml:mrow> </mml:msup> </mml:mrow> <mml:annotation>$$ {}^{23} $$</mml:annotation></mml:semantics> </mml:math> Na <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:semantics> <mml:mrow><mml:msup><mml:mo> </mml:mo> <mml:mrow><mml:mn>39</mml:mn></mml:mrow> </mml:msup> </mml:mrow> <mml:annotation>$$ {}^{39} $$</mml:annotation></mml:semantics> </mml:math> K-TiCEPT. A discrepancy can be observed in the 50-200 MHz range, but the data aligns with literature from 200-600 MHz. These results show substantial intersubject differences in effective conductivity (29%), supporting the need for an accurate method to provide in vivo dielectric tissue properties.
Authors
- Teresa Gerhalter (ORCID: https://orcid.org/0000-0001-9734-4632)
- Kemal Sümser (ORCID: https://orcid.org/0000-0002-6695-2659)
- Margarethus M. Paulides (ORCID: https://orcid.org/0000-0002-5891-2139)
- Armin Michael Nagel (ORCID: https://orcid.org/0000-0003-0948-1421)
- Rob Mestrom (ORCID: https://orcid.org/0000-0002-1971-8691)
- Laura J. C. Barendsz
Institutions
- German Cancer Research Center (DE)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Medical University of Graz (AT)
- Heidelberg University (DE)
- Erasmus MC (NL)
- Universitätsklinikum Erlangen (DE)
- Erasmus MC Cancer Institute (NL)
- Eindhoven University of Technology (NL)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1002/mrm.70139
- Primary Topic
- Electrical and Bioimpedance Tomography
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek