Nanostructured Magnesium Oxide for Swiss Mice Tissue Application: Synthesis, Characterization, and Analysis

ABSTRACT Rosemary extract produced nanoscale magnesium oxide (MgO) using a green synthesis methodology, specifically a chemical co‐precipitation process. This work investigates the effects of nanoscale MgO on Swiss mice. Fourier transform infrared (FTIR) and scanning electron microscopy (SEM) are used to characterize the synthesized material. Nano‐MgO is administered orally to mice, and then the liver and kidney tissues are examined histologically to evaluate its biological effects. The results demonstrated the remarkable biological activity of nanoscale MgO, revealing a clear inhibitory effect on these organs. According to the findings, nanoscale MgO may be useful and suitable for biomedical applications, especially for targeted inhibition in kidney and liver tissues without causing serious toxicity risks.