Survival outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer patients

NACT patients have worse survival, compared with their ACT counterparts. Although patients with pCR after NACT derive significant survival benefits, NACT-disfavored subgroups may gain limited benefit from NACT, and alternative approaches should be considered.

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Publication Details

Journal
The Oncologist
Published
2025-10-19
DOI
https://doi.org/10.1093/oncolo/oyaf356
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Survival outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer patients

Purong Zhang, Juecai Chen, Junjie Li, Chengshi Wang et al.
The Oncologist
Breast Cancer Treatment Studies
article

Survival outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer patients

Purong Zhang, Juecai Chen, Junjie Li, Chengshi Wang, Xiaoyan Zhang, Jianhui Zhang, Songbo Zhang
article en

Abstract

NACT patients have worse survival, compared with their ACT counterparts. Although patients with pCR after NACT derive significant survival benefits, NACT-disfavored subgroups may gain limited benefit from NACT, and alternative approaches should be considered.

The OncologistVol. 30(11)
Sichuan University (CN), West China Second University Hospital of Sichuan University (CN), Sichuan Cancer Hospital (CN), First Affiliated Hospital of Chengdu Medical College (CN)
Openalex Percentile: Top 63%
Breast Cancer Treatment Studies
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