The ethanol extract derived from mung bean reduced immune suppression, intestinal injury, and disruptions in gut microbiota caused by cyclophosphamide in mice
Our findings highlight the multifaceted protective benefits of MBE in counteracting CTX-induced immune suppression and intestinal damage. We found that MBE exerts prebiotic effects by restoring gut microbiota balance and enhancing probiotic activity likely via quorum sensing modulation. These findings highlight its potential as a dietary supplement to synergize with probiotics for gut-immune health during chemotherapy. © 2025 Society of Chemical Industry.
Authors
- Zhiqiang Huang (ORCID: https://orcid.org/0000-0001-7809-3241)
- Jinlin Guo (ORCID: https://orcid.org/0000-0001-9091-7100)
- Yixin Liu (ORCID: https://orcid.org/0000-0002-1627-7720)
- Sijing Liu (ORCID: https://orcid.org/0000-0001-6684-8248)
- Xiaojun Cao (ORCID: https://orcid.org/0000-0001-5670-8196)
- Jing Bai (ORCID: https://orcid.org/0000-0002-3170-2035)
- Caihong Shen
- Shuqi Niu (ORCID: https://orcid.org/0000-0003-1356-5708)
- Zhengyue Liao
Institutions
- Solid State Physics Laboratory (IN)
- Luye Pharma (China) (CN)
- First People's Hospital of Chongqing (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of the Science of Food and Agriculture
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1002/jsfa.70265
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00