Structural connectivity of striatal subregions in first-episode schizophrenia: links to positive symptoms and treatment response
These findings highlight the critical role of striatal subregions in the pathophysiology of schizophrenia, emphasising the associative striatum's involvement in cognitive control and salience attribution. Changes in striatal connectivity after continued antipsychotic therapy may serve as a biomarker for symptom improvement, advancing our understanding of schizophrenia and guiding future therapeutic strategies.
Authors
- Kai Yuan (ORCID: https://orcid.org/0000-0002-3098-1124)
- Ruini Sun
- Yuanqiang Zhu (ORCID: https://orcid.org/0000-0002-8448-7922)
- Wenming Liu (ORCID: https://orcid.org/0000-0002-7044-1130)
- Chen Wang (ORCID: https://orcid.org/0000-0002-7410-0923)
- Fan Guo (ORCID: https://orcid.org/0000-0001-8232-4102)
- Min Guo (ORCID: https://orcid.org/0000-0003-2915-1745)
- Min Cai (ORCID: https://orcid.org/0000-0003-0027-0150)
Institutions
- Xidian University (CN)
- Xijing Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- The British Journal of Psychiatry
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1192/bjp.2025.10434
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00