Molecular epidemiology of carbapenem-resistant <i>Escherichia coli</i> in a tertiary hospital located in the Dabie Mountains region, China
This represents the first systematic investigation of CREc epidemiology in this understudied region. Our results demonstrate a high prevalence of carbapenem resistance mediated primarily by <i>bla</i> <sub>NDM-5</sub>, with co-occurrence of other resistance genes (<i>fosA3</i>) and virulence factors (<i>fimH</i>/<i>hlyE</i>/<i>csgA</i>).
Authors
- Ying Jing (ORCID: https://orcid.org/0000-0003-4901-2478)
- Yuanhong Xu (ORCID: https://orcid.org/0000-0002-1637-3800)
- Runan Zhang
- Lu Wang (ORCID: https://orcid.org/0000-0002-0184-9570)
- Wanxian Gong
- Jie Zhang (ORCID: https://orcid.org/0000-0001-9210-4154)
Institutions
- Capital Medical University (CN)
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Beijing Children’s Hospital (CN)
- Lu'an First People's Hospital (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-10-24
- DOI
- https://doi.org/10.7717/peerj.20188
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00