Cervical cancer prediction using deformable kernel darknet-53 and depth wise separable convolutional neural networks

The prediction of Cervical Cancer (CC) remains a tough task due to diverse clinical variations and unbalanced data distribution, while good-quality data remains limited. Early CC signs tend to lack distinct characteristics, which makes their precise identification more challenging for medical professionals. Different methods of diagnosis integrated with the unique attributes of different datasets make it difficult to apply a uniform model to generalized patient populations. To address these issues, this paper introduces the Deformable Kernel Darknet-53 with Depth-Wise Separable Convolutional Neural Network (DK-D53-DWSCNNet). This framework initiates with image enhancement and quality adaptation for diverse heterogeneous morphological structures using Deformable Kernel Networks for Joint Image Filtering (DKNet-JIF). An ensemble Darknet-53 Convolutional Neural Network with a Contextual Attention Network (D53-CNN-CAN) is used to perform segmentation, which improves the representation of variable lesion patterns. A hybrid GAT-DWSCNNet, which merges geometric algebra transformers (GAT) with depth-wise separable CNNs, is used for feature extraction and classification, allowing the system to capture both edge and contextual features while reducing redundancy. The Hyperbolic Sine Optimizer (HSO) optimizes model training by providing the best trade-off between convergence speed and accuracy. With an accuracy of 99.9% and sensitivity of 99.8%, the experiments on the Herlev and SEER datasets depict remarkable generalization. These findings demonstrate the potential of DK-D53-DWSCNNet in improving early and robust CC prediction across different datasets, supporting the model to be embedded in clinical diagnostic procedures.

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Publication Details

Journal
Scientific Reports
Published
2025-10-24
DOI
https://doi.org/10.1038/s41598-025-21119-x
Primary Topic
AI in cancer detection
Type
article
Field-Weighted Citation Impact
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article

Cervical cancer prediction using deformable kernel darknet-53 and depth wise separable convolutional neural networks

Gaurav Ameta, T. M. Yunus Khan, G. Jenifa, Mohamed Ghouse et al.
Scientific Reports
AI in cancer detection
article

Cervical cancer prediction using deformable kernel darknet-53 and depth wise separable convolutional neural networks

Gaurav Ameta, T. M. Yunus Khan, G. Jenifa, Mohamed Ghouse, Mohammad Amir Khan, M. Sivaramkrishnan, M. Siva Ramkumar, Adis Abebaw Dessalegn, Nivethitha Thangavelsamy
article en

Abstract

The prediction of Cervical Cancer (CC) remains a tough task due to diverse clinical variations and unbalanced data distribution, while good-quality data remains limited. Early CC signs tend to lack distinct characteristics, which makes their precise identification more challenging for medical professionals. Different methods of diagnosis integrated with the unique attributes of different datasets make it difficult to apply a uniform model to generalized patient populations. To address these issues, this paper introduces the Deformable Kernel Darknet-53 with Depth-Wise Separable Convolutional Neural Network (DK-D53-DWSCNNet). This framework initiates with image enhancement and quality adaptation for diverse heterogeneous morphological structures using Deformable Kernel Networks for Joint Image Filtering (DKNet-JIF). An ensemble Darknet-53 Convolutional Neural Network with a Contextual Attention Network (D53-CNN-CAN) is used to perform segmentation, which improves the representation of variable lesion patterns. A hybrid GAT-DWSCNNet, which merges geometric algebra transformers (GAT) with depth-wise separable CNNs, is used for feature extraction and classification, allowing the system to capture both edge and contextual features while reducing redundancy. The Hyperbolic Sine Optimizer (HSO) optimizes model training by providing the best trade-off between convergence speed and accuracy. With an accuracy of 99.9% and sensitivity of 99.8%, the experiments on the Herlev and SEER datasets depict remarkable generalization. These findings demonstrate the potential of DK-D53-DWSCNNet in improving early and robust CC prediction across different datasets, supporting the model to be embedded in clinical diagnostic procedures.

Scientific ReportsVol. 15(1)
Thi Qar University (IQ), Sri Ramakrishna Institute of Paramedical Sciences (IN), Parul University (IN), La Maddalena (IT), Karpagam Academy of Higher Education (IN), King Khalid University (SA), Debre Markos University (ET)
Openalex Percentile: Top 84%
AI in cancer detection
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