Advances in cholera toxin inhibitor design: insights from molecular modelling
Targeting the B-pentamer pore, A1 active site, or A1-ARF6 interface holds significant therapeutic potential against cholera-induced dehydration and hypovolaemic shock. These underexplored yet promising druggable targets warrant further investigation for developing effective, targeted therapies.
Authors
- Abhijit Datta (ORCID: https://orcid.org/0009-0000-8227-4627)
- Aditi Gangopadhyay (ORCID: https://orcid.org/0000-0002-1951-8462)
Institutions
- University of Calcutta (IN)
- Department of Commerce (AU)
Publication Details
- Journal
- Expert Opinion on Drug Discovery
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1080/17460441.2025.2578001
- Primary Topic
- Lipid Membrane Structure and Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00