Efficacy of adjunctive antidepressants in treating negative symptoms of schizophrenia: a systematic review and network meta-analysis
These findings suggest that adjunctive use of mirtazapine and duloxetine can effectively improve the negative symptoms of schizophrenia in patients who are stably receiving antipsychotic treatment. Therefore, incorporating antidepressants into future treatment plans for negative symptoms of schizophrenia is a promising strategy that warrants further exploration.
Authors
- Kezhi Liu (ORCID: https://orcid.org/0000-0003-4515-4209)
- Rongfang He
- Minglan Yu
- Yang He (ORCID: https://orcid.org/0000-0002-0695-8039)
- Lu Shi (ORCID: https://orcid.org/0000-0003-4811-1271)
- Yuting Li (ORCID: https://orcid.org/0000-0002-6716-358X)
- Tingting Wang (ORCID: https://orcid.org/0000-0002-1774-1783)
- Wei Dong (ORCID: https://orcid.org/0000-0002-9636-9608)
- Bo Xiang
- Xuemei Liang (ORCID: https://orcid.org/0000-0002-8860-1681)
Institutions
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- Brain (Germany) (DE)
Publication Details
- Journal
- Psychological Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1017/s0033291725101803
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00