Comparative assessment of early neointimal formation: P8RI-coated Silk Vista versus Pipeline Vantage (Shield) in a rabbit model using optical coherence tomography

P8RI-SV demonstrated higher rates of neointimal formation covering the FD struts compared with bare-SV and Shield-PV at day 5 and day 28 in rabbits. These results confirm faster and improved arterial healing with P8RI coating; however, further studies are needed to evaluate the clinical benefits in patients.

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Publication Details

Journal
Journal of NeuroInterventional Surgery
Published
2025-10-23
DOI
https://doi.org/10.1136/jnis-2025-024213
Primary Topic
Aortic aneurysm repair treatments
Type
article
Field-Weighted Citation Impact
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article

Comparative assessment of early neointimal formation: P8RI-coated Silk Vista versus Pipeline Vantage (Shield) in a rabbit model using optical coherence tomography

Ludovic Micallef, Maxime Baudouin, Nicolas Dubois, Laurent Spelle et al.
Journal of NeuroInterventional Surgery
Aortic aneurysm repair treatments
article

Comparative assessment of early neointimal formation: P8RI-coated Silk Vista versus Pipeline Vantage (Shield) in a rabbit model using optical coherence tomography

Ludovic Micallef, Maxime Baudouin, Nicolas Dubois, Laurent Spelle, Aymeric Rouchaud, Alexis Belgacem, Faraj Terro, V. Ratsimbazafy, Charbel Mounayer, Jonathan Cortese, Sylvia M. Bardet, Jérémy Mounier, M Coulomb, Romain Chauvet, Francesco Diana, Aurélien Le Flahec, Sylvain Dulaurent, Géraud Forestier, Édouard Lefebvre, Daphnée Chandellier, Gregory Sasselina, Claude Couquet, Marie Laure Perrin, M. D’Arrigo, Caroline Croguennec
article en

Abstract

P8RI-SV demonstrated higher rates of neointimal formation covering the FD struts compared with bare-SV and Shield-PV at day 5 and day 28 in rabbits. These results confirm faster and improved arterial healing with P8RI coating; however, further studies are needed to evaluate the clinical benefits in patients.

Journal of NeuroInterventional Surgery
Hebron University (PS), Centre National de la Recherche Scientifique (FR), Inserm (FR), Université Paris-Saclay (FR), Vall d'Hebron Institut de Recerca (ES), Centre Hospitalier Universitaire de Limoges (FR), Vall d'Hebron Hospital Universitari (ES), Institut d’Epidémiologie Neurologique et de Neurologie Tropicale (FR), Bicêtre Hospital (FR), Institut de Recherche pour le Développement (FR), Université de Limoges (FR)
Openalex Percentile: Top 56%
Aortic aneurysm repair treatments
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