Baicalin protects retinal ganglion cells by regulating microglial polarization and ferroptosis via the JAK2/STAT3 pathway
This study reveals that baicalin protects RGCs by modulating microglial polarization and inhibiting ferroptosis, providing novel insights for the treatment of glaucoma.
Authors
- Jun Zou (ORCID: https://orcid.org/0000-0003-2443-3516)
- Tianzhao Xu
- Feng Qian (ORCID: https://orcid.org/0000-0001-5766-4623)
- Yilin Wang (ORCID: https://orcid.org/0000-0002-4432-7545)
- Huan Yu (ORCID: https://orcid.org/0009-0000-9863-0585)
- Xiaoyun Ma (ORCID: https://orcid.org/0000-0002-9821-0617)
Institutions
- Tongji University (CN)
- Shanghai Tenth People's Hospital (CN)
- Shanghai University of Medicine and Health Sciences (CN)
- Community Health Center (US)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-10-24
- DOI
- https://doi.org/10.3389/fphar.2025.1660294
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00