Progression characteristics of biliary atresia during the waiting period for liver transplantation: a single-center observational study

This study provides unprecedented quantification of the rapid natural progression of BA cirrhosis, revealing a critical 3 month window of clinical deterioration. The dynamic changes in routinely available laboratory markers, particularly neutrophil percentage and ammonia, offer clinically accessible indicators for risk stratification and monitoring, forming a practical "dashboard" for managing BA patients awaiting transplantation in resource-varied settings.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-10-24
DOI
https://doi.org/10.3389/fmed.2025.1679733
Primary Topic
Pediatric Hepatobiliary Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Progression characteristics of biliary atresia during the waiting period for liver transplantation: a single-center observational study

Mingman Zhang, Chenyu Yang, Jianyang Hu, Ruijue Wang et al.
Frontiers in Medicine
Pediatric Hepatobiliary Diseases and Treatments
article

Progression characteristics of biliary atresia during the waiting period for liver transplantation: a single-center observational study

Mingman Zhang, Chenyu Yang, Jianyang Hu, Ruijue Wang, Qiang Xiong, Kenneth Boon Kiat Tan, Ying Le, Xiaoke Dai, Jiqiang Hu
article en

Abstract

This study provides unprecedented quantification of the rapid natural progression of BA cirrhosis, revealing a critical 3 month window of clinical deterioration. The dynamic changes in routinely available laboratory markers, particularly neutrophil percentage and ammonia, offer clinically accessible indicators for risk stratification and monitoring, forming a practical "dashboard" for managing BA patients awaiting transplantation in resource-varied settings.

Frontiers in MedicineVol. 12
Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 52%
Pediatric Hepatobiliary Diseases and Treatments
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