Overcoming barriers to off-patent drug repurposing: a lifecycle-based policy solutions
Off-patent drug repurposing faces persistent financial and regulatory barriers that require a central role from academics and non-profit sponsors, supported by governmental engagement throughout the lifecycle. Although steps have been taken in recent years, efforts remain insufficient, and structural and political barriers continue to hinder broader implementation.
Authors
- Jaime Espín (ORCID: https://orcid.org/0000-0001-7299-6554)
- David Epstein
- Mario Garcia-Diaz
Institutions
- Universidad de Granada (ES)
- Instituto de Investigación Biosanitaria de Granada (ES)
- Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES)
- Andalusian School of Public Health (ES)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-10-24
- DOI
- https://doi.org/10.3389/fphar.2025.1670845
- Citations
- 1
- Primary Topic
- Pharmaceutical Economics and Policy
- Type
- article
- Field-Weighted Citation Impact
- 3.13