Adipose-derived stem cells alleviate radiation-induced muscle fibrosis by promoting muscle regeneration
Our study provides evidence that ADSCs protect against RIF by promoting SC activation, proliferation, and differentiation <i>in vivo</i>. ADSCs may represent a promising therapeutic candidate for restoring muscle dysfunction and abnormalities caused by RIF.
Authors
- Yuxin Ge
- Zhijiao Zhou (ORCID: https://orcid.org/0000-0002-2282-7397)
- Luyuan Xie
- Xiaowu Sheng (ORCID: https://orcid.org/0000-0002-0558-6616)
- Chunmeng Shi (ORCID: https://orcid.org/0000-0002-8264-738X)
- Sha Li (ORCID: https://orcid.org/0000-0002-4869-3809)
- Zehong Song
- Xiao Zhou (ORCID: https://orcid.org/0000-0002-6155-7860)
- Mingjing Peng
- Xiang Ou
Institutions
- Central South University (CN)
- Army Medical University (CN)
- Changsha Medical University (CN)
- Changsha Central Hospital (CN)
- Hunan Cancer Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
- Third Xiangya Hospital (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-10-24
- DOI
- https://doi.org/10.3389/fcell.2025.1620998
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00