Serial T1 and T2 measurements of metastatic bone lesions in prostate cancer patients: MR fingerprinting vs conventional MRI
Question MR fingerprinting (MRF)-derived T<sub>1</sub> and T<sub>2</sub> values have the potential to characterise bone metastasis and treatment response, but their performance against conventional MRI is unclear. Findings The inter-method reproducibility coefficient was 19.3% for T<sub>1</sub> and 32.5% for T<sub>2</sub>, whilst the Spearman correlation coefficient was strong for both parameters. Clinical relevance Serial MRF-derived T<sub>1</sub> and T<sub>2</sub> measurements in bone metastasis in patients with prostate cancer correlated well with conventional MRI measurements, supporting MRF use for faster quantitative measurements in bone lesions.
Authors
- Jessica Winfield (ORCID: https://orcid.org/0000-0001-6069-5252)
- Erica Scurr
- Julie Hughes (ORCID: https://orcid.org/0000-0003-3380-696X)
- Matthew Orton (ORCID: https://orcid.org/0000-0002-0805-763X)
- Dow‐Mu Koh (ORCID: https://orcid.org/0000-0001-7654-8011)
- Nina Tunariu (ORCID: https://orcid.org/0000-0001-6656-3699)
- Georgina Hopkinson (ORCID: https://orcid.org/0000-0003-4967-8886)
- Vikas Gulani (ORCID: https://orcid.org/0000-0003-0889-5999)
- Mihaela Rata (ORCID: https://orcid.org/0000-0003-4999-8038)
- Yun Jiang (ORCID: https://orcid.org/0000-0002-0713-9641)
Institutions
- Royal Marsden NHS Foundation Trust (GB)
- Institute of Cancer Research (GB)
- University of Michigan (US)
Publication Details
- Journal
- European Radiology
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1007/s00330-025-12071-5
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Royal Marsden NHS Foundation Trust
- Cancer Research UK
- National Institute for Health and Care Research
- Department of Health and Social Care