Leiomyosarcoma of Lip: An Exceptional Variant of Lip Malignancy

Soft-tissue sarcomas constitute rare malignant tumours of the head and neck region. Leiomyosarcoma presents with varied clinical presentations and is usually misdiagnosed as carcinomas. Hence, their definite diagnosis is on histopathology along with immunohistochemical analysis. We have reported a case of a 57-year-old man with a tumour of the lower lip for the past 1 year. He underwent a wide local excision and Estlander flap lip reconstruction. A histological and immunohistochemical study showed the presence of dermal leiomyosarcoma. The origin of primary dermal cutaneous leiomyosarcoma can be the piloerector muscle, the smooth muscle of the sweat glands or the dartos muscle. The hypodermal form derives from the smooth muscle of the wall of cutaneous arterioles and venules. Primary cutaneous leiomyosarcoma is preferentially located on the extensor surfaces of the lower limbs and rarely affects the oral cavity.