Impact of Pre‐Heart Transplant Levosimendan Administration on Post‐Transplant Vasoplegia and Primary Graft Dysfunction
This study evaluated whether giving levosimendan before HT affects early post-transplant complications. Among 598 patients, 94 received levosimendan within a month before surgery. Results showed no significant differences in rates of vasoplegia, severe primary graft dysfunction, or mortality. Levosimendan use appears safe in the immediate pre-transplant setting.
Authors
- Andrea Arenas‐Loriente (ORCID: https://orcid.org/0000-0002-5313-2379)
- Mercedes Rivas‐Lasarte (ORCID: https://orcid.org/0000-0002-8704-3104)
- Ana García‐Álvarez (ORCID: https://orcid.org/0000-0002-1718-2424)
- J. Segovia-Cubero
- Marta Farrero (ORCID: https://orcid.org/0000-0002-2404-8821)
- David Couto‐Mallón (ORCID: https://orcid.org/0000-0002-1112-4063)
- Joan Guzmán-Bofarull (ORCID: https://orcid.org/0000-0001-6064-8683)
- Roger Borràs (ORCID: https://orcid.org/0000-0002-8585-2522)
- Alba Martín‐Centellas (ORCID: https://orcid.org/0000-0002-2375-0643)
- María G. Crespo‐Leiro (ORCID: https://orcid.org/0000-0002-4886-5615)
Institutions
- Spanish National Centre for Cardiovascular Research (ES)
- Centro de Investigación en Red en Enfermedades Cardiovasculares (ES)
- Departament de Salut (ES)
- Hospital Universitario Puerta de Hierro Majadahonda (ES)
- Centro de Investigación Biomédica en Red (ES)
- Hospital Clínic de Barcelona (ES)
- Instituto de Investigación Biomédica de A Coruña (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Clinical Transplantation
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1111/ctr.70327
- Citations
- 2
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Fundación Alfonso Martín Escudero
- Sociedad Española de Cardiología
- Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares