Acute exercise alters immune responses in older adults, with extracellular vesicle changes observed in a high-intensity intervention
Acute exercise modulates immune responses in an intensity- and sex-dependent manner in older adults. Extracellular vesicle release was assessed only in the high-intensity intervention, where significant changes were observed. These findings support personalized exercise regimens to enhance immune resilience and promote healthy aging.
Authors
- Ildikò Rita Dunay (ORCID: https://orcid.org/0000-0002-9900-8605)
- Alejandra P. Garza (ORCID: https://orcid.org/0000-0002-2993-7679)
- Lorena Morton (ORCID: https://orcid.org/0000-0002-3957-3848)
- Christian Puta (ORCID: https://orcid.org/0000-0003-3936-4605)
- S. Chakrabarty
- Ruediger C. Braun‐Dullaeus (ORCID: https://orcid.org/0000-0003-3888-6532)
- A Motsch
- Marvin Stiebler (ORCID: https://orcid.org/0000-0002-3654-7265)
- Edit I. Buzás (ORCID: https://orcid.org/0000-0002-3744-206X)
- Stefanie Schreiber (ORCID: https://orcid.org/0000-0003-4439-4374)
- Patrick Müller
- Yves Lading
Institutions
- Semmelweis University (HU)
- German Center for Neurodegenerative Diseases (DE)
- Institute of Materials and Environmental Chemistry (HU)
- Center for Behavioral Brain Sciences (DE)
- German Center for Lung Research (DE)
- Montavid Thermodynamic Research Group (HU)
- Jena University Hospital (DE)
- IntellADAPT (United States) (US)
- University Hospital Magdeburg (DE)
- Heinrich Heine University Düsseldorf (DE)
- Friedrich Schiller University Jena (DE)
- Otto-von-Guericke-Universität Magdeburg (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-24
- DOI
- https://doi.org/10.3389/fimmu.2025.1661161
- Citations
- 2
- Primary Topic
- Exercise and Physiological Responses
- Type
- article
- Field-Weighted Citation Impact
- 2.05
Funders
- Novartis Foundation
- Bundesministerium für Bildung und Forschung
- European Regional Development Fund