Monochorionic-specific association between first-trimester serum ferritin and gestational diabetes in twin pregnancies: a retrospective cohort study

Elevated SF levels in early pregnancy are independently associated with a higher risk of GDM in MCDA twin pregnancies and may serve as a potential early biomarker for GDM prediction. In contrast, no significant association was found in DCDA pregnancies, indicating that the predictive value of SF may differ by chorionicity. Further studies are warranted to confirm these findings and investigate the underlying mechanisms.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-10-24
DOI
https://doi.org/10.3389/fendo.2025.1616668
Primary Topic
Gestational Diabetes Research and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Monochorionic-specific association between first-trimester serum ferritin and gestational diabetes in twin pregnancies: a retrospective cohort study

Xiping Xu, Yanyan Ni, Jue Ma, Yan Bi et al.
Frontiers in Endocrinology
Gestational Diabetes Research and Management
article

Monochorionic-specific association between first-trimester serum ferritin and gestational diabetes in twin pregnancies: a retrospective cohort study

Xiping Xu, Yanyan Ni, Jue Ma, Yan Bi, Yuanling Hu, Yanlin Wang
article en

Abstract

Elevated SF levels in early pregnancy are independently associated with a higher risk of GDM in MCDA twin pregnancies and may serve as a potential early biomarker for GDM prediction. In contrast, no significant association was found in DCDA pregnancies, indicating that the predictive value of SF may differ by chorionicity. Further studies are warranted to confirm these findings and investigate the underlying mechanisms.

Frontiers in EndocrinologyVol. 16
International Peace Maternity & Child Health Hospital (CN)
Shanghai Municipal Health Commission, Science and Technology Commission of Shanghai Municipality, Shanghai Jiao Tong University
Openalex Percentile: Top 62%
Gestational Diabetes Research and Management
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