MutSeqR: an open source R package for standardized analysis of error-corrected next-generation sequencing data in genetic toxicology
MutSeqR is freely available under an open source license at https://github.com/EHSRB-BSRSE-Bioinformatics/MutSeqR. Implemented in R (version 3.4.0 or greater), it supports all major operating systems. Sequencing data for Project 1 has been deposited in the Sequence Read Archive under accession number PRJNA803048. Variant call files for Project 2 are available on Mendeley Data (doi: 10.17632/65dnysxym8.1).
Authors
- A. Williams (ORCID: https://orcid.org/0000-0001-9080-0105)
- Charles C. Valentine (ORCID: https://orcid.org/0000-0001-5630-7368)
- Annette Dodge (ORCID: https://orcid.org/0000-0002-0446-9055)
- Jesse J. Salk (ORCID: https://orcid.org/0000-0002-7804-0550)
- E. N. Esina (ORCID: https://orcid.org/0000-0002-1685-2406)
- Francesco Marchetti (ORCID: https://orcid.org/0000-0002-9435-4867)
- Carole L. Yauk (ORCID: https://orcid.org/0000-0002-6725-3454)
- Danielle P M LeBlanc (ORCID: https://orcid.org/0000-0002-3847-8371)
- Michael Meier (ORCID: https://orcid.org/0000-0002-8443-7618)
- Alexander Y. Maslov (ORCID: https://orcid.org/0000-0001-5402-8891)
- Chris P. Bradley (ORCID: https://orcid.org/0000-0001-6554-1463)
- David M. Schuster (ORCID: https://orcid.org/0009-0001-6316-4358)
Institutions
- Health Canada (CA)
- Albert Einstein College of Medicine (US)
- University of Ottawa (CA)
- University of Washington (US)
- BioWorks (United States) (US)
- Fulcrum Therapeutics (United States) (US)
- Syngenta (China) (CN)
- Carleton University (CA)
Publication Details
- Journal
- Bioinformatics Advances
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1093/bioadv/vbaf265
- Primary Topic
- Carcinogens and Genotoxicity Assessment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canada Research Chairs
- Health Canada
- Natural Sciences and Engineering Research Council of Canada