Novel BMP2K::PDGFRA fusion in an unusual myeloid/lymphoid neoplasm with eosinophilia

Given that PDGFRA fusions with novel fusion partners may respond to tyrosine kinase inhibitor therapy, partner agnostic testing methods should be considered either up front or as reflex testing in patients with myeloid and/or lymphoid neoplasms with blood, bone marrow, or tissue eosinophilia.

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Publication Details

Journal
Journal of Hematopathology
Published
2025-10-24
DOI
https://doi.org/10.1007/s12308-025-00661-7
Primary Topic
Eosinophilic Disorders and Syndromes
Type
article
Field-Weighted Citation Impact
0.00
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article

Novel BMP2K::PDGFRA fusion in an unusual myeloid/lymphoid neoplasm with eosinophilia

Sophia Yohe, Mehrnoosh Tashakori, Ravi Tej Bommu, Laila O. Mnayor
Journal of Hematopathology
Eosinophilic Disorders and Syndromes
article

Novel BMP2K::PDGFRA fusion in an unusual myeloid/lymphoid neoplasm with eosinophilia

Sophia Yohe, Mehrnoosh Tashakori, Ravi Tej Bommu, Laila O. Mnayor
article en

Abstract

Given that PDGFRA fusions with novel fusion partners may respond to tyrosine kinase inhibitor therapy, partner agnostic testing methods should be considered either up front or as reflex testing in patients with myeloid and/or lymphoid neoplasms with blood, bone marrow, or tissue eosinophilia.

Journal of HematopathologyVol. 18(1)
Hartford Hospital (US), University of Minnesota (US), University of Iowa Health Care (US)
Openalex Percentile: Top 56%
Eosinophilic Disorders and Syndromes
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