Pepsin, trypsin, and MUC5B are independent risk factors for hearing impairment in patients with laryngopharyngeal reflux-related chronic secretory otitis media
Pepsin, trypsin, and MUC5B are independent risk factors for hearing impairment in LPR-related CSOM patients. Their combination assists hearing impairment diagnosis in patients, providing a tool in clinical practice to stratify patients and offering a theoretical basis for exploring therapeutic targets.
Authors
- Ying Cao (ORCID: https://orcid.org/0000-0002-4289-452X)
- Junpeng Qiu (ORCID: https://orcid.org/0009-0001-6736-3389)
- De Huai
- Hongmao Song (ORCID: https://orcid.org/0000-0002-5764-3846)
Institutions
- Xuzhou Medical College (CN)
- Second People’s Hospital of Huai’an (CN)
- Changzhou Third People's Hospital (CN)
Publication Details
- Journal
- Expert Review of Clinical Immunology
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1080/1744666x.2025.2575363
- Citations
- 1
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 1.16