Decompressive Craniectomy With Abdominal Bone Flap Preservation in Herpes Simplex Encephalitis: A Case Report

Herpes simplex encephalitis (HSE) is a rare but severe condition that can lead to significant morbidity and mortality. Although antiviral therapy with acyclovir has improved outcomes, some patients develop complications such as focal hemorrhagic necrosis and edema in the temporal lobe, with subsequent elevation of intracranial pressure (ICP) and uncal herniation, necessitating surgical intervention. We report a pediatric case of HSE with life-threatening ICP refractory to sedation, osmotic therapy, and moderate hyperventilation. Despite aggressive treatment, the patient underwent a left-sided decompressive hemicraniectomy, with the bone flap preserved in a subcutaneous abdominal pocket, a technique shown in previous studies to maintain bone viability and minimize infection risk. This approach effectively controlled ICP and allowed progressive neurological recovery. At three-month follow-ups, the patient demonstrated favorable neurological outcomes (Glasgow Outcome Scale = 5) with successful autologous cranial reconstruction.

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Journal
Cureus
Published
2025-10-23
DOI
https://doi.org/10.7759/cureus.95262
Primary Topic
Herpesvirus Infections and Treatments
Type
article
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article

Decompressive Craniectomy With Abdominal Bone Flap Preservation in Herpes Simplex Encephalitis: A Case Report

Eugenia Espinosa, Ricardo Marlon Saro Del Valle, Irenilce Souza de Matos, Javier de la Peña et al.
Cureus
Herpesvirus Infections and Treatments
article

Decompressive Craniectomy With Abdominal Bone Flap Preservation in Herpes Simplex Encephalitis: A Case Report

Eugenia Espinosa, Ricardo Marlon Saro Del Valle, Irenilce Souza de Matos, Javier de la Peña, Idalberto Luis Fernandez Eng
article en

Abstract

Herpes simplex encephalitis (HSE) is a rare but severe condition that can lead to significant morbidity and mortality. Although antiviral therapy with acyclovir has improved outcomes, some patients develop complications such as focal hemorrhagic necrosis and edema in the temporal lobe, with subsequent elevation of intracranial pressure (ICP) and uncal herniation, necessitating surgical intervention. We report a pediatric case of HSE with life-threatening ICP refractory to sedation, osmotic therapy, and moderate hyperventilation. Despite aggressive treatment, the patient underwent a left-sided decompressive hemicraniectomy, with the bone flap preserved in a subcutaneous abdominal pocket, a technique shown in previous studies to maintain bone viability and minimize infection risk. This approach effectively controlled ICP and allowed progressive neurological recovery. At three-month follow-ups, the patient demonstrated favorable neurological outcomes (Glasgow Outcome Scale = 5) with successful autologous cranial reconstruction.

CureusVol. 17(10)
Universidad de la República de Uruguay (UY), Clinique des Cèdres (FR), HealthCare Partners Medical Group (US), Hospital de La Ribera (ES), Hospital Oncológico Docente "Conrado Benítez García" (CU), Arista (United States) (US)
Openalex Percentile: Top 59%
Herpesvirus Infections and Treatments
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Decompressive Craniectomy With Abdominal Bone Flap Preservation in Herpes Simplex Encephalitis: A Case Report — Eugenia Espinosa, Ricardo Marlon Saro Del Valle, et al. · Cureus (2025) | TGRS Research Map | TGRS