Overcoming chemoresistance in non-small cell lung cancer: Insights into the influence of inflammatory factors on treatment response
These findings demonstrated that IL-6 and related cytokines contribute to DDP resistance in NSCLC. IL-6 inhibition restores chemosensitivity and may serve as a promising therapeutic strategy in resistant NSCLC.
Authors
- Yue Dai (ORCID: https://orcid.org/0000-0002-1773-5228)
- Juan Feng (ORCID: https://orcid.org/0000-0003-0174-4784)
- Nian Cao
- Xi Tian (ORCID: https://orcid.org/0000-0003-1965-0647)
- Jianqiang Xu (ORCID: https://orcid.org/0000-0002-1289-5943)
- Zhenzhen Hu (ORCID: https://orcid.org/0000-0001-7020-3071)
- Yayun Liu (ORCID: https://orcid.org/0000-0002-5949-0695)
Institutions
- China Three Gorges University (CN)
- Gezhouba Central Hospital of Sinopharm (CN)
Publication Details
- Journal
- World Journal of Clinical Oncology
- Published
- 2025-10-24
- DOI
- https://doi.org/10.5306/wjco.v16.i10.112097
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.94