Human epidermal growth factor receptor 2 overexpression is associated with high-grade tumors in upper tract urothelial carcinoma

In UTUC, HER2 overexpression is closely associated with tumor dedifferentiation (high grade), while it does not correlate with conventional indicators of disease progression, indicating that HER2 may serve a distinct biological function in this cancer type.

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Publication Details

Journal
World Journal of Clinical Oncology
Published
2025-10-24
DOI
https://doi.org/10.5306/wjco.v16.i10.110047
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Human epidermal growth factor receptor 2 overexpression is associated with high-grade tumors in upper tract urothelial carcinoma

Lin Huang, Juan He
World Journal of Clinical Oncology
Bladder and Urothelial Cancer Treatments
article

Human epidermal growth factor receptor 2 overexpression is associated with high-grade tumors in upper tract urothelial carcinoma

Lin Huang, Juan He
article en

Abstract

In UTUC, HER2 overexpression is closely associated with tumor dedifferentiation (high grade), while it does not correlate with conventional indicators of disease progression, indicating that HER2 may serve a distinct biological function in this cancer type.

World Journal of Clinical OncologyVol. 16(10)
Guangxi Medical University (CN), First Affiliated Hospital of GuangXi Medical University (CN)
Openalex Percentile: Top 52%
Bladder and Urothelial Cancer Treatments
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Human epidermal growth factor receptor 2 overexpression is associated with high-grade tumors in upper tract urothelial carcinoma — Lin Huang, Juan He · World Journal of Clinical Oncology (2025) | TGRS Research Map | TGRS