The impact of response latency on working memory assessment in mice

MK-801 impairs working memory and alters response latency, effects which are independent from each other, which isolates a true effect of this drug on working memory performance. We recommend similar regression analyses are conducted in future studies to rule out confounding effects of response latencies on task performance.

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Publication Details

Journal
Experimental Neurology
Published
2025-10-23
DOI
https://doi.org/10.1016/j.expneurol.2025.115525
Primary Topic
Memory and Neural Mechanisms
Type
article
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article

The impact of response latency on working memory assessment in mice

Gwonhyu Jin, Nigel C. Jones, Rachel Hill, Chitra Vinnakota et al.
Experimental Neurology
Memory and Neural Mechanisms
article

The impact of response latency on working memory assessment in mice

Gwonhyu Jin, Nigel C. Jones, Rachel Hill, Chitra Vinnakota, Duong Nhu, Suresh Sundram, Yonghong Liu, Matthew R. Hudson, Louise Inger
article en

Abstract

MK-801 impairs working memory and alters response latency, effects which are independent from each other, which isolates a true effect of this drug on working memory performance. We recommend similar regression analyses are conducted in future studies to rule out confounding effects of response latencies on task performance.

Experimental NeurologyVol. 396
The University of Melbourne (AU), Monash University (AU)
Openalex Percentile: Top 70%
Memory and Neural Mechanisms
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