Visible‐Light Induced Metal‐Free Organophotocatalyzed Synthesis of Biologically Active Benzofuran Derivatives

ABSTRACT A straightforward, safe, and effective visible light‐mediated metal‐free organophotocatalyzed process has been developed to synthesize potentially bioactive substituted benzofuran scaffolds. This synthetic protocol uses visible light‐mediated acridinium as a photocatalyst to catalyze the cycloaddition reaction between substituted phenol and diphenyl acetylene following photoredox conditions at room temperature. Gentle reaction conditions, good to exceptional results, high atom economy, environmentally benign procedures, apparent reaction conditions, and the suitability for large‐scale synthesis are a few of the specific features of this current synthetic protocol.