Whole Blood in the Management of Postpartum Hemorrhage

Whole blood (WB) has been shown to improve outcomes in military acute trauma patients and, to a limited extent, in civilian trauma and acute obstetric hemorrhage. The objective of this study was to examine maternal outcomes in patients receiving WB compared with <i>component therapy</i> (defined as packed red blood cells with plasma) for postpartum hemorrhage (PPH). Fifty-two patients met inclusion criteria. The WB group required fewer total blood products, intravenous fluids, and repeated operative procedures. This report demonstrates the potential benefit for use of WB in cases of acute PPH.

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Publication Details

Journal
O&G Open
Published
2025-10-01
DOI
https://doi.org/10.1097/og9.0000000000000130
Primary Topic
Trauma, Hemostasis, Coagulopathy, Resuscitation
Type
article
Field-Weighted Citation Impact
0.00
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article

Whole Blood in the Management of Postpartum Hemorrhage

Kristen Warncke, Alesha White, April Gorman, Elaine L. Duryea et al.
O&G Open
Trauma, Hemostasis, Coagulopathy, Resuscitation
article

Whole Blood in the Management of Postpartum Hemorrhage

Kristen Warncke, Alesha White, April Gorman, Elaine L. Duryea, R. Nicholas Burns, Anne M. Ambía, David Nelson
article en

Abstract

Whole blood (WB) has been shown to improve outcomes in military acute trauma patients and, to a limited extent, in civilian trauma and acute obstetric hemorrhage. The objective of this study was to examine maternal outcomes in patients receiving WB compared with <i>component therapy</i> (defined as packed red blood cells with plasma) for postpartum hemorrhage (PPH). Fifty-two patients met inclusion criteria. The WB group required fewer total blood products, intravenous fluids, and repeated operative procedures. This report demonstrates the potential benefit for use of WB in cases of acute PPH.

O&G OpenVol. 2(5)
Southwestern Medical Center (US), Southwestern Medical Center (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 65%
Trauma, Hemostasis, Coagulopathy, Resuscitation
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