Deciphering the dialogue between the bovine blastocyst and the uterus: embryo-induced alterations in extracellular vesicle protein content from an ex vivo model and the in vivo environment
These findings highlight the pivotal role of EVs in embryo-maternal communication, suggesting that their protein cargo may actively contribute to the modulation of the uterine environment to support early embryonic development. Understanding these molecular interactions could provide valuable insights into the mechanisms of implantation and pregnancy establishment.
Authors
- Sandra Guisado Egido
- Alberto Álvarez (ORCID: https://orcid.org/0000-0003-4761-0212)
- Esperanza González (ORCID: https://orcid.org/0000-0002-3831-4596)
- Rosane Mazzarella (ORCID: https://orcid.org/0000-0001-6860-8897)
- Michael McDonald (ORCID: https://orcid.org/0000-0002-4063-4441)
- Juan Manuel Falcón‐Pérez (ORCID: https://orcid.org/0000-0003-3133-0670)
- Dimitrios V. Rizos (ORCID: https://orcid.org/0000-0001-6813-3940)
- Beatriz Fernández-Fuertes (ORCID: https://orcid.org/0000-0003-2303-8733)
- Mikel Azkargorta (ORCID: https://orcid.org/0000-0001-9115-3202)
- José María Sánchez (ORCID: https://orcid.org/0000-0003-3889-2342)
- P. Lonergan (ORCID: https://orcid.org/0000-0001-5598-5044)
- M. E. González
Institutions
- University College Dublin (IE)
- Ikerbasque (ES)
- Universidad Complutense de Madrid (ES)
- Consejo Superior de Investigaciones Científicas (ES)
- CIC bioGUNE (ES)
- Centro de Investigación Biomédica en Red (ES)
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (ES)
- Universidad de Extremadura (ES)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1186/s40104-025-01270-1
- Citations
- 1
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 1.88