A Review of Physiological Characteristics and their Resultant Effect on the Jaundice Level

Early delivery of neonates and reduction in birth weight, according to researchers, are mostly caused by jaundice in neonates, while yellowish color of the skin, yellowness of the eyes, and fingertips are its most common clinically visible symptoms as the age after birth increases. Jaundice results from high bilirubin levels and is a common condition particularly among neonates and persons with hepatic dysfunction. This paper reviews some physiological characteristics (e.g., yellowish color of the skin, gestation period, yellowness of the eyes, age of the child, weight of the child, etc.) and establishes if the level of jaundice would have a negative effect on them. Statistical analysis shows the significant inverse correlation between bilirubin levels and both birth weight and gestation duration and suggests that a lower infant birth weight is associated with a high jaundice level. A regression analysis establishes the gestational age and chronological age as significant predictors of birth weight, with the bilirubin’s effect, though inversely related, having no statistical significance. Longer gestation and older age predict higher birth weight. Although bilirubin negatively impacts weight, it’s not a strong predictor in the model. Finally, the bilirubin level may not be clinically revealed immediately after delivery and may also result in low birth weight and preterm delivery, and their relationship, if properly analyzed with hybrid machine learning tools, mathematical modeling and object-oriented programming language, can serve as a building block for a model that would diagnose jaundice non-invasively. These findings from this research provide a fundamental basis for clinicians in the prediction and management of jaundice risk based on physiological characteristics