National Cancer Institute's Working Group on Biochemically Recurrent Prostate Cancer: Clinical Trial Design Considerations
These discussions should inform future clinical BCR trials in this distinct disease space relative to metastatic disease defined by conventional imaging. The NCI BCR WG strongly advocates that future trials explore deintensification of treatment to minimize toxicity in this relatively indolent disease state.
Authors
- Michael A. Carducci (ORCID: https://orcid.org/0000-0002-7908-1215)
- Krishnan R. Patel (ORCID: https://orcid.org/0000-0003-2120-1939)
- Meredith M. Regan (ORCID: https://orcid.org/0000-0002-2428-6109)
- Melissa L. Abel (ORCID: https://orcid.org/0000-0001-8941-0206)
- Douglas G. McNeel (ORCID: https://orcid.org/0000-0003-1471-6723)
- David Johnson Einstein (ORCID: https://orcid.org/0000-0001-9163-3281)
- Edwin M. Posadas (ORCID: https://orcid.org/0000-0001-8649-1346)
- Jeanny B. Aragon‐Ching (ORCID: https://orcid.org/0000-0002-6714-141X)
- Julie N. Graff (ORCID: https://orcid.org/0000-0002-5708-2794)
- Laura A. Sena (ORCID: https://orcid.org/0000-0001-6724-9546)
- Xiao X. Wei (ORCID: https://orcid.org/0000-0001-7093-0383)
- Ravi Amrit Madan (ORCID: https://orcid.org/0000-0001-5106-8636)
- Mark Christopher Markowski (ORCID: https://orcid.org/0000-0003-2780-5100)
- Marijo Bilušić (ORCID: https://orcid.org/0000-0003-1020-689X)
- Susan Halabi (ORCID: https://orcid.org/0000-0003-4135-2777)
- Catherine Handy Marshall (ORCID: https://orcid.org/0000-0002-2653-4110)
- Fatima Karzai (ORCID: https://orcid.org/0000-0002-3244-1332)
- Esther Mena (ORCID: https://orcid.org/0000-0003-0015-0597)
- Phuoc T. Tran (ORCID: https://orcid.org/0000-0002-0147-0376)
- James L. Gulley (ORCID: https://orcid.org/0000-0002-6569-2912)
- Philip M. Arlen
- Deborah E. Citrin (ORCID: https://orcid.org/0000-0002-4391-2734)
- William D. Figg (ORCID: https://orcid.org/0000-0003-2428-5613)
- Liza Lindenberg (ORCID: https://orcid.org/0000-0002-8514-0648)
- Peter L. Choyke (ORCID: https://orcid.org/0000-0003-1086-8826)
- Charlotte S. Walmsley
- Russell K. Pachynski (ORCID: https://orcid.org/0000-0002-8966-7631)
- Evan Y. Yu (ORCID: https://orcid.org/0000-0002-1510-8044)
- Kenneth J. Pienta (ORCID: https://orcid.org/0000-0002-4138-2186)
- Channing Judith Paller (ORCID: https://orcid.org/0000-0003-3658-1858)
- Karen A. Autio (ORCID: https://orcid.org/0000-0003-0720-0390)
- Helen Moon (ORCID: https://orcid.org/0009-0007-6303-5285)
Institutions
- University of Maryland, Baltimore (US)
- Cedars-Sinai Medical Center (US)
- Beth Israel Deaconess Medical Center (US)
- Memorial Sloan Kettering Cancer Center (US)
- University of Wisconsin–Madison (US)
- Johns Hopkins University (US)
- University of Miami (US)
- Duke University (US)
- Washington University in St. Louis (US)
- Portland VA Medical Center (US)
- Fred Hutch Cancer Center (US)
- Virginia Cancer Institute (US)
- Sidney Kimmel Cancer Center (US)
- Kaiser Permanente Riverside Medical Center (US)
- Dana-Farber Cancer Institute (US)
- National Cancer Institute (US)
- Center for Cancer Research (US)
- Sidney Kimmel Comprehensive Cancer Center (US)
Publication Details
- Journal
- Journal of Clinical Oncology
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1200/jco-25-01693
- Citations
- 3
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 4.56