Familial Hypercholesterolemia in Pediatric Patients With Type 1 Diabetes: Double Challenge for Diagnosis and Treatment

The prevalence of probable FH was high (1 in 215 children) in pediatric T1D. We assume that the majority are affected by genetic FH, modified by HbA1c and BMI. Despite the very high risk for premature atherosclerosis in patients with FH and T1D, only one-third receive LLT.

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Publication Details

Journal
Diabetes Care
Published
2025-10-23
DOI
https://doi.org/10.2337/dc25-1195
Primary Topic
Diabetes Treatment and Management
Type
article
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article

Familial Hypercholesterolemia in Pediatric Patients With Type 1 Diabetes: Double Challenge for Diagnosis and Treatment

Jantje Weiskorn, Sven Golembowski, Thomas Meißner, Reinhard W. Holl et al.
Diabetes Care
Diabetes Treatment and Management
article

Familial Hypercholesterolemia in Pediatric Patients With Type 1 Diabetes: Double Challenge for Diagnosis and Treatment

Jantje Weiskorn, Sven Golembowski, Thomas Meißner, Reinhard W. Holl, Susanna Wiegand, Marianne Becker, Dagmar Meraner, E. Schulz, Karl Otfried Schwab, Markus Röbl
article en

Abstract

The prevalence of probable FH was high (1 in 215 children) in pediatric T1D. We assume that the majority are affected by genetic FH, modified by HbA1c and BMI. Despite the very high risk for premature atherosclerosis in patients with FH and T1D, only one-third receive LLT.

Diabetes CareVol. 48(12)
Innsbruck Medical University (AT), Centre Hospitalier de Luxembourg (LU), Zimmer Biomet (Netherlands) (NL), Universität Ulm (DE), University Medical Center Freiburg (DE), Kinderkrankenhaus auf der Bult (DE), Victoria University of Bangladesh (BD), Düsseldorf University Hospital (DE), Sana Klinikum Lichtenberg (DE), Dermatologie Freiburg (DE), Kinderkrebs-Zentrum Hamburg (DE), Universitätsmedizin Göttingen (DE), Deutsches Diabetes-Zentrum e.V. (DE), German Center for Diabetes Research (DE), Heinrich Heine University Düsseldorf (DE), University of Göttingen (DE), Charité - Universitätsmedizin Berlin (DE)
Openalex Percentile: Top 58%
Diabetes Treatment and Management
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Familial Hypercholesterolemia in Pediatric Patients With Type 1 Diabetes: Double Challenge for Diagnosis and Treatment — Jantje Weiskorn, Sven Golembowski, et al. · Diabetes Care (2025) | TGRS Research Map | TGRS