Limitations of hormonal and clinical markers in predicting GnRH agonist trigger success in polycystic ovary syndrome: A critical reappraisal
A high AFC was the only identifiable predictor of the OPF rate and a suboptimal response when a GnRH agonist trigger was used for final follicular maturation. However, since a low AUC for AFC suggests a poor performance, we conclude that this study was not able to find any reliable prediction markers for the OPF rate in PCOS patients triggered with GnRHa.
Authors
- Peter Humaidan (ORCID: https://orcid.org/0000-0001-6884-5366)
- Fazilet Kübra Boynukalın (ORCID: https://orcid.org/0000-0002-4721-2786)
- Mustafa Bahçeci (ORCID: https://orcid.org/0000-0002-5626-3251)
- Gürkan Bozdağ (ORCID: https://orcid.org/0000-0002-6679-9623)
- Özkan Özdamar (ORCID: https://orcid.org/0000-0001-9730-0285)
- Meral Gültomruk (ORCID: https://orcid.org/0000-0002-2898-5468)
- Zalihe Yarkıner (ORCID: https://orcid.org/0000-0002-4766-6454)
Institutions
- Üsküdar University (TR)
- Bahçeşehir University (TR)
- Cyprus International University (CY)
- Aarhus University (DK)
- Skive Hospital (DK)
- Final International University (CY)
- University of Kyrenia (CY)
- Turkish Air Force Academy (TR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1371/journal.pone.0332813
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00