Curcumin attenuates LPS-induced inflammation in RAW 264.7 cells: A multifaceted study integrating network pharmacology, molecular docking, molecular dynamics simulation, and experimental validation

Our study provides a comprehensive understanding of curcumin's anti-inflammatory mechanisms through an integrated approach. The findings highlight curcumin's potential as a therapeutic agent for inflammatory diseases. However, further in vivo studies are necessary to fully elucidate its therapeutic efficacy and mechanisms of action.

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Publication Details

Journal
PLoS ONE
Published
2025-10-23
DOI
https://doi.org/10.1371/journal.pone.0335139
Citations
3
Primary Topic
Curcumin's Biomedical Applications
Type
article
Field-Weighted Citation Impact
1.77
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article

Curcumin attenuates LPS-induced inflammation in RAW 264.7 cells: A multifaceted study integrating network pharmacology, molecular docking, molecular dynamics simulation, and experimental validation

Xiaojing Gong, Bing Xie, Chuanbo Zang, Lihua Zhao et al.
3 citations
PLoS ONE
Curcumin's Biomedical Applications
1.77
article

Curcumin attenuates LPS-induced inflammation in RAW 264.7 cells: A multifaceted study integrating network pharmacology, molecular docking, molecular dynamics simulation, and experimental validation

Xiaojing Gong, Bing Xie, Chuanbo Zang, Lihua Zhao, Hongyan Meng, Xue Deng, Jiong Kong
article en
3 citations

Abstract

Our study provides a comprehensive understanding of curcumin's anti-inflammatory mechanisms through an integrated approach. The findings highlight curcumin's potential as a therapeutic agent for inflammatory diseases. However, further in vivo studies are necessary to fully elucidate its therapeutic efficacy and mechanisms of action.

PLoS ONEVol. 20(10)
Qingdao Binhai University (CN)
Openalex Percentile: Top 14%
Curcumin's Biomedical Applications
1.77
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