Curcumin attenuates LPS-induced inflammation in RAW 264.7 cells: A multifaceted study integrating network pharmacology, molecular docking, molecular dynamics simulation, and experimental validation
Our study provides a comprehensive understanding of curcumin's anti-inflammatory mechanisms through an integrated approach. The findings highlight curcumin's potential as a therapeutic agent for inflammatory diseases. However, further in vivo studies are necessary to fully elucidate its therapeutic efficacy and mechanisms of action.
Authors
- Xiaojing Gong (ORCID: https://orcid.org/0000-0002-8221-3522)
- Bing Xie (ORCID: https://orcid.org/0000-0003-2335-5966)
- Chuanbo Zang
- Lihua Zhao
- Hongyan Meng
- Xue Deng
- Jiong Kong
Institutions
- Qingdao Binhai University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1371/journal.pone.0335139
- Citations
- 3
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.77