Identification of clinical phenotypes in Behçet's syndrome using latent class analysis: a step toward precision medicine

This study is the first to apply LCA for BS clinical phenotyping, providing a probabilistic classification that uncovers complex patient subgroups. Five latent classes were identified, with distinct clinical profiles, significant sex disparities, and varying therapeutic needs. These findings are crucial for advancing precision medicine in BS and ultimately improving patient outcomes.

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Publication Details

Journal
Clinical and Experimental Rheumatology
Published
2025-10-23
DOI
https://doi.org/10.55563/clinexprheumatol/3dhh59
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of clinical phenotypes in Behçet's syndrome using latent class analysis: a step toward precision medicine

M. Maamar, Z. Tazi Mezalek, Rédouane Abouqal, Sarra Chadli et al.
Clinical and Experimental Rheumatology
Ocular Diseases and Behçet’s Syndrome
article

Identification of clinical phenotypes in Behçet's syndrome using latent class analysis: a step toward precision medicine

M. Maamar, Z. Tazi Mezalek, Rédouane Abouqal, Sarra Chadli, H. Harmouche, Wafaa Ammouri
article en

Abstract

This study is the first to apply LCA for BS clinical phenotyping, providing a probabilistic classification that uncovers complex patient subgroups. Five latent classes were identified, with distinct clinical profiles, significant sex disparities, and varying therapeutic needs. These findings are crucial for advancing precision medicine in BS and ultimately improving patient outcomes.

Clinical and Experimental RheumatologyVol. 43(10)
Mohammed V University (MA), Ibn Sina Hospital (KW)
Openalex Percentile: Top 56%
Ocular Diseases and Behçet’s Syndrome
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