Association between anti-nuclear antibody (ANA) positivity and autoimmune thyroid disease markers in a general examination population
Elevated thyroid autoantibodies (TPOAb, TgAb) are strongly associated with increased ANA positivity risk, suggesting a link between thyroid-specific and systemic autoimmunity. Thyroid hormone levels showed minimal association. Patients with high TPOAb/TgAb, especially females, may benefit from ANA screening.
Authors
- Qian Gong (ORCID: https://orcid.org/0000-0001-7747-6953)
- Wanjun Yu (ORCID: https://orcid.org/0000-0003-1583-9047)
- Yue Lei
- Mengjiao Yuan
- Jinjin Wang (ORCID: https://orcid.org/0000-0001-8382-044X)
- Jianmin Lin
Institutions
- Sun Yat-sen University (CN)
- Fudan University (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Biochemistry and Biophysics Reports
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1016/j.bbrep.2025.102330
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00