Clinical and genomic characteristics of HER2-ultralow breast cancer and implications for T-DXd therapy

In conclusion, HER2-ultralow status is not associated with distinct clinicopathologic or genomic characteristics. HER2-IHC 0 (MS-) and ultralow statuses often coexist within the same patient.

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Publication Details

Journal
Precision Clinical Medicine
Published
2025-10-13
DOI
https://doi.org/10.1093/pcmedi/pbaf026
Citations
1
Primary Topic
HER2/EGFR in Cancer Research
Type
article
Field-Weighted Citation Impact
1.05
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article

Clinical and genomic characteristics of HER2-ultralow breast cancer and implications for T-DXd therapy

Hong Lv, Biyun Wang, Zhonghua Tao, Leiping Wang et al.
1 citations
Precision Clinical Medicine
HER2/EGFR in Cancer Research
1.05
article

Clinical and genomic characteristics of HER2-ultralow breast cancer and implications for T-DXd therapy

Hong Lv, Biyun Wang, Zhonghua Tao, Leiping Wang, Juan Jin, Xichun Hu, Mengyuan Cai, Hongxia Wang, Tiantian Liu, Wentao Yang, Mingchuan Zhao, Duanchen Guo
article en
1 citations

Abstract

In conclusion, HER2-ultralow status is not associated with distinct clinicopathologic or genomic characteristics. HER2-IHC 0 (MS-) and ultralow statuses often coexist within the same patient.

Precision Clinical MedicineVol. 8(4)
Shanghai Medical College of Fudan University (CN), Fudan University Shanghai Cancer Center (CN)
Openalex Percentile: Top 17%
HER2/EGFR in Cancer Research
1.05
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