Transcriptomic Insights into Polyomavirus Nephropathy in Kidney Transplants: Evaluating the Utility of the Banff Human Organ Transplant Panel
The B-HOT panel provides limited utility for diagnosing PyVN beyond viral gene quantification. However, T-cell checkpoint signaling may serve as a prognostic marker for viral clearance and renal function preservation in PyVN cases. Further studies are needed to refine molecular diagnostics for PyVN and improve transplant outcomes.
Authors
- Tatsu Tanabe (ORCID: https://orcid.org/0009-0003-6167-9774)
- Yuko Katayama
- Koji Taniguchi (ORCID: https://orcid.org/0000-0002-8091-6005)
- Takako Yamaguchi
- Kanako C. Hatanaka (ORCID: https://orcid.org/0009-0008-9596-9661)
- Shugo Tanaka
- Yasushi Ishii (ORCID: https://orcid.org/0000-0001-5893-8032)
- Takahiro Tsuji (ORCID: https://orcid.org/0000-0001-9810-7305)
- Daigo Nakazawa
- Masayoshi Miura (ORCID: https://orcid.org/0000-0002-8469-5326)
- Hajime Sasaki (ORCID: https://orcid.org/0000-0001-7639-0912)
- Satoshi Tanaka (ORCID: https://orcid.org/0009-0001-3257-1639)
- Hiroshi Harada (ORCID: https://orcid.org/0000-0001-5121-6686)
- Sari Iwasaki (ORCID: https://orcid.org/0000-0002-2075-1122)
- Satoshi Aoyama (ORCID: https://orcid.org/0000-0003-0262-6026)
Institutions
- Sapporo University (JP)
- Hokkaido University (JP)
- Sapporo Hokuyu Hospital (JP)
- Sapporo City General Hospital (JP)
Publication Details
- Journal
- The Nephron journals/Nephron journals
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1159/000549068
- Primary Topic
- Polyomavirus and related diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00