What Changes First? Mapping the Temporal Ordering of Age-Related Functional Decline across Domains Using 30-Year Longitudinal Data
The study offers insights into early detection and prevention strategies for healthy aging. Assuming that physical and cognitive domains are primarily driven by age-related biological changes, our findings support theories proposing that biological changes precede functional decline and theories emphasizing the importance of psychosocial resilience. Moreover, this study highlights the potential of adopting a complex systems approach and innovative within-person analytical methods in gerontology. .
Authors
- Almar A. L. Kok (ORCID: https://orcid.org/0000-0001-6398-2484)
- Erik J. Giltay (ORCID: https://orcid.org/0000-0001-8874-2292)
- Martijn Huisman (ORCID: https://orcid.org/0000-0002-9285-6759)
- Gabriela Lunansky (ORCID: https://orcid.org/0000-0001-6226-2258)
- Marjolein Visser (ORCID: https://orcid.org/0000-0002-5136-298X)
Institutions
- Leiden University Medical Center (NL)
- Public Health Service of Amsterdam (NL)
- Amsterdam University Medical Centers (NL)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Gerontology
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1159/000548990
- Citations
- 1
- Primary Topic
- Health disparities and outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.17
Funders
- Amsterdam University Medical Centers
- ZonMw
- Vrije Universiteit Amsterdam