Glucagon-Like Peptide-1 Receptor Agonists and Age-Related Macular Degeneration

In this cohort study, GLP-1RA use was associated with reduced risk of developing nonexudative AMD but was not associated with progression to exudative AMD among individuals with nonexudative AMD. These findings may inform future randomized trials evaluating the ocular effects of GLP-1RAs in nondiabetic populations.

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Publication Details

Journal
JAMA Ophthalmology
Published
2025-10-23
DOI
https://doi.org/10.1001/jamaophthalmol.2025.3821
Citations
5
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
6.47
Controls
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article

Glucagon-Like Peptide-1 Receptor Agonists and Age-Related Macular Degeneration

Benjamin K. Young, Alfredo A Paredes, Abhimanyu S. Ahuja
5 citations
JAMA Ophthalmology
Diabetes Treatment and Management
6.47
article

Glucagon-Like Peptide-1 Receptor Agonists and Age-Related Macular Degeneration

Benjamin K. Young, Alfredo A Paredes, Abhimanyu S. Ahuja
article en
5 citations

Abstract

In this cohort study, GLP-1RA use was associated with reduced risk of developing nonexudative AMD but was not associated with progression to exudative AMD among individuals with nonexudative AMD. These findings may inform future randomized trials evaluating the ocular effects of GLP-1RAs in nondiabetic populations.

JAMA OphthalmologyVol. 143(12)
Oregon Health & Science University (US), Florida Atlantic University (US)
Openalex Percentile: Top 3%
Diabetes Treatment and Management
6.47
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