Integrating Multimodal Neuroimaging of Error Monitoring to Estimate Future Anxiety in Adolescents
This cohort study found that integrating multimodal neuroimaging measures of error monitoring was associated with improved estimations of future anxiety in youths over and above each modality separately. Early temperament interacted with error monitoring to further differentiate anxiety trajectories; yet, these interactions differed across brain regions, highlighting the value of incorporating the complementary temporal and spatial information of EEG and fMRI.
Authors
- Anderson M. Winkler (ORCID: https://orcid.org/0000-0002-4169-9781)
- Daniel S. Pine (ORCID: https://orcid.org/0000-0002-4301-9516)
- Marco McSweeney (ORCID: https://orcid.org/0000-0002-6873-6917)
- Santiago Morales (ORCID: https://orcid.org/0000-0002-9850-042X)
- Lauren K. White (ORCID: https://orcid.org/0000-0002-6394-4768)
- John E. Richards (ORCID: https://orcid.org/0000-0002-8283-4468)
- Elise M. Cardinale (ORCID: https://orcid.org/0000-0002-5117-6124)
- Stefania Conte (ORCID: https://orcid.org/0000-0002-8249-3288)
- Lucrezia Liuzzi (ORCID: https://orcid.org/0000-0003-2344-5187)
- Emilio A. Valadez (ORCID: https://orcid.org/0000-0002-6614-8628)
- George A. Buzzell (ORCID: https://orcid.org/0000-0003-3324-3183)
- Enda Tan (ORCID: https://orcid.org/0000-0002-0512-848X)
- Yi Feng (ORCID: https://orcid.org/0000-0002-3487-908X)
- Nathan A. Fox
Institutions
- University of Southern California (US)
- Binghamton University (US)
- Florida Department of Children and Families (US)
- Children's Hospital of Philadelphia (US)
- University of British Columbia (CA)
- University of South Carolina (US)
- University of California, Los Angeles (US)
- University of America (US)
- The University of Texas Rio Grande Valley (US)
- University of Pennsylvania Health System (US)
- Lifespan (US)
- National Institute of Mental Health (US)
- University of Maryland, College Park (US)
- Catholic University of America (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.39133
- Citations
- 1
- Primary Topic
- Child and Adolescent Psychosocial and Emotional Development
- Type
- article
- Field-Weighted Citation Impact
- 2.31
Funders
- National Institutes of Health
- National Institute of Mental Health