Assessment of RLEP Copy Number in Leprosy Patient Skin Biopsies: Correlations With Cytokine and Anti-PGL-1 Antibody Levels Pre- and Post-Treatment
qPCR is a sensitive diagnostic test, and in conjunction with anti-PGL-1 antibody and cytokine levels, clinical and histomorphologic features can be used for the appropriate classification of leprosy, diagnosis of atypical cases, disease monitoring, and risk prediction of leprosy reactions.
Authors
- Itu Singh (ORCID: https://orcid.org/0000-0003-0596-8566)
- Rashmi Joshi (ORCID: https://orcid.org/0000-0003-1807-7674)
- Biman Saikia (ORCID: https://orcid.org/0000-0001-7181-6064)
- Manoj Gopal Madakshira (ORCID: https://orcid.org/0000-0002-7056-5096)
- Bishan Dass Radotra (ORCID: https://orcid.org/0000-0001-6198-7521)
- S. Dogra (ORCID: https://orcid.org/0000-0002-0812-0758)
- Tarun Narang
Institutions
- The Leprosy Mission International (GB)
- Post Graduate Institute of Medical Education and Research (IN)
Publication Details
- Journal
- American Journal of Dermatopathology
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1097/dad.0000000000003161
- Primary Topic
- Leprosy Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00