Comprehensive investigation of the molecular basis of cancer dependencies suggests therapeutic options for breast cancer

We established a DMA analysis pipeline linking the gene dependencies of breast cancer cell lines to multi-omics characteristics, thus elucidating the underpinnings of tumor dependencies and offering a valuable resource for developing novel precision treatment strategies incorporating relevant markers.

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Publication Details

Journal
Cancer Biology and Medicine
Published
2025-10-23
DOI
https://doi.org/10.20892/j.issn.2095-3941.2025.0290
Primary Topic
Bioinformatics and Genomic Networks
Type
article
Field-Weighted Citation Impact
0.00
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article

Comprehensive investigation of the molecular basis of cancer dependencies suggests therapeutic options for breast cancer

Zhi‐Ming Shao, Rui Ding, Tian‐Jian Yu
Cancer Biology and Medicine
Bioinformatics and Genomic Networks
article

Comprehensive investigation of the molecular basis of cancer dependencies suggests therapeutic options for breast cancer

Zhi‐Ming Shao, Rui Ding, Tian‐Jian Yu
article en

Abstract

We established a DMA analysis pipeline linking the gene dependencies of breast cancer cell lines to multi-omics characteristics, thus elucidating the underpinnings of tumor dependencies and offering a valuable resource for developing novel precision treatment strategies incorporating relevant markers.

Cancer Biology and MedicineVol. 22(12)
Shanghai Medical College of Fudan University (CN), Fudan University Shanghai Cancer Center (CN)
Openalex Percentile: Top 73%
Bioinformatics and Genomic Networks
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