Hyperproduction of 3-hydroxybutyrate using engineered probiotic <i>E. coli</i> Nissle 1917 from glucose and CO <sub>2</sub> -derived acetate
Hyperproduction of 3-HB (105 g L −1 ) was achieved using recombinant EcN with glucose and CO 2 -derived acetate with a significantly reduced carbon footprint.
Authors
- Chun-Xiao Yan
- Rong Deng (ORCID: https://orcid.org/0000-0003-2005-7517)
- Linda Yu
- Yang Fu-he (ORCID: https://orcid.org/0000-0002-0365-366X)
- Yi-Hao Deng (ORCID: https://orcid.org/0009-0007-0889-5434)
- Jianwen Ye (ORCID: https://orcid.org/0000-0003-2562-7283)
- Wei Situ
- Huaiming Wang (ORCID: https://orcid.org/0000-0002-3409-0927)
- Hongwei Shen (ORCID: https://orcid.org/0000-0001-8151-7316)
- Hui Wang (ORCID: https://orcid.org/0000-0003-1450-6320)
- Jinyan Lv
- Zheng Ye (ORCID: https://orcid.org/0000-0001-5532-6428)
- Xia Lin (ORCID: https://orcid.org/0000-0003-0928-5287)
- Yina Lin
Institutions
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- Yingkou Institute of Technology (CN)
- China General Nuclear Power Corporation (China) (CN)
- Beike Biotechnology (China) (CN)
- Kai Biotech (South Korea) (KR)
- Guangdong Food and Drug Vocational College (CN)
- South China University of Technology (CN)
Publication Details
- Journal
- Green Chemistry
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1039/d5gc03448e
- Primary Topic
- Microbial Metabolic Engineering and Bioproduction
- Type
- article
- Field-Weighted Citation Impact
- 0.00