Successful Management of Delayed Postoperative Hemorrhage Following Chalazion Excision Using Oral Tranexamic Acid

A 59-year-old man presented with bilateral chalazia refractory to conservative management. Following excision, histopathology confirmed the diagnosis. Seven days postoperatively, he developed spontaneous, painless bleeding from the left upper eyelid. Follow-up examination suggested a small pyogenic granuloma, which was excised, but recurrent hemorrhage persisted. Further hematologic workup was unremarkable. A short course of oral tranexamic acid was initiated, leading to complete resolution of bleeding within 24 hours. Delayed hemorrhage following chalazion excision is rare, with limited cases reported, and this case demonstrates successful noninvasive management with oral tranexamic acid. While tranexamic acid is widely used in major surgeries, its role in minor ophthalmic procedures remains off-label. This case supports its potential utility as a hemostatic agent in select ophthalmic cases, warranting further investigation into its efficacy and safety in this context.

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Publication Details

Journal
Ophthalmic Plastic and Reconstructive Surgery
Published
2025-10-23
DOI
https://doi.org/10.1097/iop.0000000000003104
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
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article

Successful Management of Delayed Postoperative Hemorrhage Following Chalazion Excision Using Oral Tranexamic Acid

Trisha Miglani, Payal Patel
Ophthalmic Plastic and Reconstructive Surgery
Glaucoma and retinal disorders
article

Successful Management of Delayed Postoperative Hemorrhage Following Chalazion Excision Using Oral Tranexamic Acid

Trisha Miglani, Payal Patel
article en

Abstract

A 59-year-old man presented with bilateral chalazia refractory to conservative management. Following excision, histopathology confirmed the diagnosis. Seven days postoperatively, he developed spontaneous, painless bleeding from the left upper eyelid. Follow-up examination suggested a small pyogenic granuloma, which was excised, but recurrent hemorrhage persisted. Further hematologic workup was unremarkable. A short course of oral tranexamic acid was initiated, leading to complete resolution of bleeding within 24 hours. Delayed hemorrhage following chalazion excision is rare, with limited cases reported, and this case demonstrates successful noninvasive management with oral tranexamic acid. While tranexamic acid is widely used in major surgeries, its role in minor ophthalmic procedures remains off-label. This case supports its potential utility as a hemostatic agent in select ophthalmic cases, warranting further investigation into its efficacy and safety in this context.

Ophthalmic Plastic and Reconstructive Surgery
Manhattan Institute for Policy Research (US), NYU Langone Health (US)
Openalex Percentile: Top 56%
Glaucoma and retinal disorders
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